IFNG and tuberculosis: Since that there is an extensive literature [8, 9, 19, 20] regarding the evaluation of PF biomarkers showing that the TB’s lymphocytic pleural effusion presents an increased expression of interferon-γ (IFN-γ) and its inducible chemokines, such as interferon-γ inducible protein of 10-kD (IP-10) [19, 21], we speculate that the application of IGRA could be extremely promising and show considerable adjuvant value on diagnosis of paucibacillary patients.