She also presented 36,000 red blood cells count in PF, which could have influenced the production and consequently, the measurement of these biomarkers; ii) a possible TB, woman, 19 years old, unknown HIV status, with an exudative and lymphocytic pleural effusion, with the highest ADA levels registered in the study (259 IU/L) and false negative results for IFN-γ and IP-10. This evidence concerns the gene IFNG and tuberculosis.