ELF3 and ovarian neoplasm: For example, recent analysis of ovarian tumours showed that ELF3 expression was restricted to epithelial cells, and that reduced ELF3 expression across tumour gene-expression panels (TCGA) correlated with poor prognosis.29 In the same study, upregulation of ELF3 in ovarian cancer cell-lines caused reduced expression of mesenchymal markers, suppression of proliferation and anchorage-dependent growth.