The expression of UCHL1 gene in skin biopsies of psoriasis patients was downregulated in comparison to group of healthy individuals (Figure 3(A)). UCHL1 expression in nonlesional psoriatic skin (mean: 0.002; SD: ±0.0008, p<0.001) was significantly lower in comparison to control group (mean: 0.008; SD: ±0.007). This evidence concerns the gene UCHL1 and psoriasis.