ABCB11 and benign recurrent intrahepatic cholestasis: There are two genetically characterised forms of BRIC: BRIC1 (Summerskill-Walshe-Tygstrup syndrome, OMIM #243300) and BRIC2 (OMIM #605479), caused by partial deficiency in ATP8B1 [39, 73] and ABCB11 [74], respectively.