IL10 and asthma: While IL-10 deficiency in BALB/c mice strongly reduces asthma-induced susceptibility (158- to 1.7-fold increase for HDM and 1,148- to 75-fold increase for Alt), this is not the case of IL-12p40 deficiency (158- to 1,324-fold increase for HDM and 1,148- to 74,131-fold increase for Alt) (Figure 8A).