Flow cytometry analysis of lung cells from control, HDM, and Alt sensitized infected transgenic mice expressing GFP under the control of the IL-10 promoter (IL-10GFP mice) showed that IL-10 is mainly produced by B cells in control mice and by B cells, CD4+ T cells, and to a lesser extent eosinophils, CD8+ T and NK1.1+ cells following asthma sensitization (Figure 9). The gene discussed is CD4; the disease is asthma.