Analysis of T-helper subsets within lesional skin showed a significantly Th2 skewed response in OVA-induced AD-like lesions of FliiTg/Tg mice with higher numbers of CD4+GATA3+ cells compared to AD-like lesions of Flii+/− or wild-type counterparts who showed significantly higher Th1:Th2 ratio. Here, GATA3 is linked to Alzheimer disease.