We found that TNFAIP2 contributes to KLF5‐induced cell adhesion, migration and invasion in breast cancer.6 TNFAIP2 interacts with the 2 small GTPases Rac1 and Cdc42 and regulates the formation of filopodia and lamellipodia, which provide force to cell motility.6 Here, CDC42 is linked to breast carcinoma.