CNOT3 and neoplasm: To determine which mRNA transcripts are affected by Not3 knockdown, we carried out RNA-sequencing analysis (Fig. 5a) on L3 larvae eye discs isolated from the sensitized parental, sensitized control (sensitized + UAS-RNAi white), and sensitized Not3-tumor eye discs: sensitized + Not3-Pelement and sensitized + UAS-RNAi Not3 knockdowns.