Moreover, western blot results confirmed that miR-203 up-regulation suppressed CSE1L expression, while miR-203-mediated inhibitory effect on CSE1L expression was reversed by BANCR overexpression in LoVo and HCT116 cells (Fig. 5I and 5J), indicating that BANCR acted as a miR-203 sponge to sequester miR-203 away from CSE1L in CRC cells. This evidence concerns the gene CSE1L and colorectal carcinoma.