PTH and hypercalcemia disease: Neonatal severe hyperparathyroidism (NSHPT) was considered, based on marked PTH elevation and periosteal abnormalities, despite the absence of hypercalcemia; pamidronate single dose Day 16 then daily cinacalcet (calcimimetic) were used preemptively to avoid anticipated severe hypercalcemia (Fisher, Cabrera, & Imel, 2015).