CD4 and TNF receptor 1-associated periodic fever syndrome: It has been reported that BM-MSCs play a therapeutic role in the pathogenesis of FHF and chronic fibrosis in mice by acting on various cells such as stimulating proliferation and inhibiting apoptosis of hepatocytes, reducing infiltrating macrophages, transforming CD4+ T lymphocytes into an anti-inflammatory state, and causing death of hepatic stellate cells [36].