HAS-2 mRNA expression was 2.3-fold greater in higher-risk MDS-MSC compared with normal MSC (p = 0.003), meanwhile, HAS-2 mRNA expression was significantly increased in higher-risk MDS-MSC compared to lower-risk MDS-MSC (p = 0.019; Fig. 2g). The gene discussed is HAS2; the disease is myelodysplastic syndrome.