Xia et al. reported that administration of emodin (1,3,8-trihydroxy-6-methyl-anthraquinone), an anthraquinone derivative from the Chinese herb Radix et Rhizoma Rhei, which reportedly suppresses inflammatory cytokine production, promoted pancreatic occludin expression, reduced pancreatic paracellular permeability, which ameliorated pancreatic injury, and exerted a protective effect against experimental AP in rats [30]. The gene discussed is OCLN; the disease is alkaline phosphatase measurement.