A total of 40 ITP patients and 41 controls were used to determine the expression level of NF-κB. A significantly lower NF-κB mRNA level was found in ITP patients (median 0.0217) compared with controls (median 0.0575, p < 0.0001. The gene discussed is NFKB1; the disease is autoimmune thrombocytopenic purpura.