TGFB3 and rickets: The risk factors for the development of UFs are better known than their etiology [1] and include elevated BMI values [1, 13, 14], positive family history [1, 4, 14], genetics [15, 16], black race [17, 18] hypovitaminosis D [14, 19, 20], soybean and food additives consumption [1], and elevated serum TGF-β3 (transforming growth factor beta 3) levels [14, 19, 21].