RB1 and hydrops fetalis: Compared to the control group, HF groups significantly reduced the ratio between PCr and ATP (PCr/ATP ratio, P=0.000) and significantly increased the ratio between ADP and ATP (ADP/ATP ratio, P=0.000), which was further worsened by Ara A (P<0.05) and significantly improved by Gs-Rb1, Aicar, and Aicar+Gs-Rb1 (P<0.05).