The mRNA expression of Cpt1b and Cpt2 was significantly downregulated in HF (P<0.05) and reduced further by Ara A (P<0.05) and upregulated by Gs-Rb1, Aicar, and Aicar+Gs-Rb1 (P<0.05) with no differences in the three groups (P>0.05). The gene discussed is ATIC; the disease is hydrops fetalis.