Finally, we compared the formation of colorectal tumors in APC+/min-CX3CR1+/- and APC+/min-CX3CR1-/- DSS-treated mice: when the CX3CR1 status was considered, we did not find any difference in the IntegriSense750 accumulation between APC+/min-CX3CR1+/- and APC+/min-CX3CR1-/- mice (data not shown). Here, APC is linked to colorectal neoplasm.