We therefore stained tissues with an anti-CD31 antibody to specifically identify vessels: white arrows in Figure 7C and 7D indicate the colocalization between IntegriSense and CD31+ vessels, confirming the expression of integrin αvβ3 by tumor-associated vessels in both small intestine and colon tumor (Figure 7C and 7D, respectively). This evidence concerns the gene PECAM1 and colonic neoplasm.