Several studies using HER2-based CAR in sarcoma (28), mesothelin-specific CAR in mesothelioma and pancreatic cancer (29–31), carcinoembryonic antigen for colorectal cancer (32), EGFRvIII in glioblastoma (33), and α-folate receptor in ovarian carcinoma (34) have shown safer toxicity profiles but yield no better treatment outcomes than stable disease in most cases. Here, ERBB2 is linked to sarcoma.