The progeroid syndromes caused by LMNA mutations encompass Hutchinson-Gilford progeria syndrome (HGPS), mandibuloacral dysplasia (MAD), Malouf syndrome, and several atypical progeroid syndromes that cannot be assigned clearly. The gene discussed is LMNA; the disease is Dilated cardiomyopathy - hypergonadotropic hypogonadism.