SLC26A9 and Meconium ileus: SLC26A9 is a key candidate in CF as it has been shown to play a pleiotropic role across CF phenotypes, associated with meconium ileus (Sun et al., 2012; Li et al., 2014), immunoreactive trypsinogen at birth (Soave et al., 2014; Miller et al., 2015), pancreatic damage (Li et al., 2014), and CFRD (Blackman et al., 2013; Soave et al., 2014).