MBP and myeloid sarcoma: Incubation of untreated blood serum from either MS patients or healthy donors with Cy5-MBP81–99-QXL680 revealed that amount of serum that is equivalent to purified IgG in terms of antibodies concentration resulted in at least ten times higher fluorescence signal (Fig. S2) compared to the MBP-hydrolyzing antibodies from the MS patients (Fig. 1e).