WNT1 and neoplasm: MMTV-Wnt1 tumour fragments were cultured with and without DMSO (vehicle controls, ROCKi, GM6001 and Canertinib inhibitors for 72 hours in either ET-SIM cultures (i.e. co-cultured with differentiated 3T3-L1 adipocyte cells) or empty scaffolds to elucidate both therapeutic efficacy and adipocyte influence on migration.