Earlier, we have also shown increased HDAC3 epigenetic signature in patients with type 2 diabetes [49], and in the present study, there was a positive correlation of HDAC3 mRNA expression with majority of the lncRNAs and this endorses the concerted and coordinated interactions between lncRNAs and histone modifications [50]. The gene discussed is HDAC3; the disease is type 2 diabetes mellitus.