However, the relatively low number of renal outcomes in our study may be consequent to a limited follow up; indeed, previous work in a large community without renal insufficiency has reported that elevated plasma levels of PTH can account for 20% of the population-attributable risk proportion for CV mortality, indicating that elevated serum PTH may have a significant prognostic effect even in the absence of renal dysfunction [34]. The gene discussed is PTH; the disease is Renal insufficiency.