In this context, another remarkable finding of our study was that the prophylactic administration of BC reduced both the gene expression of TLR4 (0.32 fold change) and of some pro-inflammatory cytokines such as Il-1β (0.29 fold change) and IL-8 (0.24 fold change) after the treatment with TNBS compared to the control group. The gene discussed is TLR4; the disease is breast cancer.