In survival analysis, lower expression of 24 hub genes (BOP1, TIGD5, C8orf76, C8orf33, FAM83H, UBR5, NSMCE2, DCAF13, PYCRL, NUDCD1, INTS8, ZNF623, TOP1MT, STIP1, HSP90AB1, PRR7, COMMD5, DSCC1, POP1, ARHGAP39, PRKDC, YDJC, PUSL1, STAU2) was associated with significantly longer OS of HCC patients. Here, PYCR3 is linked to hepatocellular carcinoma.