In survival analysis, lower expression of 24 hub genes (BOP1, TIGD5, C8orf76, C8orf33, FAM83H, UBR5, NSMCE2, DCAF13, PYCRL, NUDCD1, INTS8, ZNF623, TOP1MT, STIP1, HSP90AB1, PRR7, COMMD5, DSCC1, POP1, ARHGAP39, PRKDC, YDJC, PUSL1, STAU2) was associated with significantly longer OS of HCC patients. Here, NUDCD1 is linked to hepatocellular carcinoma.