Furthermore, 18 hub genes (TIGD5, C8ORF33, ZNF250, NUDCD1, INTS8, ZNF623, PHF20L1, STIP1, ZNF16, HSP90AB1, LRRC14, DSCC1, POP1, ARHGAP39, PRKDC, YDJC, PUSL1, UBD) showed significantly different expression levels by different tumour stages. Here, STIP1 is linked to neoplasm.