In the hematopoietic system, expression of Csde1 is increased more than 100-fold in erythroblasts relative to other hematopoietic cells, and expression of Csde1 is reduced in the congenital anemia Diamond Blackfan Anemia (DBA), characterized by haploinsufficiency of ribosomal proteins involved in ribosome biogenesis [5]. This evidence concerns the gene CSDE1 and congenital anemia.