SLC1A5 and neoplasm: Glutamine is imported into tumor cells primarily by ASCT2 (Wasa et al., 1996; Collins et al., 1998; Fuchs et al., 2007; Scalise et al., 2017), where it is used for nucleotide synthesis (Lane and Fan, 2015) and to replenish TCA cycle intermediates (Albers et al., 2012; Schulze and Harris, 2012; Pochini et al., 2014).