Microarray analyses of ZNF554-silenced cells revealed 123 DE genes (Data S13 in Supplementary Material) including 9 DE placental genes in preeclampsia, and the dysregulation of the “glycolysis/gluconeogenesis” pathway (OR = 7.8, q = 0.06) as well as 18 molecular functions including “RNA binding” (down) and “activin binding” (up) (Figure 9I; Data S14 in Supplementary Material). The gene discussed is ZNF554; the disease is preeclampsia.