SPRY4-IT1, an lncRNA overexpressed in melanoma cells, negatively regulates triacylglycerol levels in melanoma cells and knockdown of SPRY4-IT1 can induce apoptosis via lipin 2-mediated alterations in lipid metabolism leading to cellular lipotoxicity (Mazar et al., 2014). Here, HAUS3 is linked to melanoma.