Of note, although GCNT2 KD melanoma cells plated on plastic did show a slight increase in expression of prosurvival genes BCL-2 and BCL-XL (Supplementary Fig. 5d), upon engagement with ECM, GCNT2 KD melanoma cells significantly upregulated the expression of both BCL-2 and BCL-XL (Fig. 5i). Here, BCL2 is linked to melanoma.