The ability of dendritic cells (DC) to take up tumor antigens is a pivotal step in the induction of antitumor immunity, underscored by studies showing that antibody blockade of CD47, an inhibitory “don’t-eat-me” receptor upregulated on many tumor cells, potentiates the induction of protective antitumor T cell immunity in mice1,2. This evidence concerns the gene CD47 and neoplasm.