In addition, Lamorte et al. [75] compared the ability of human umbilical vein endothelial cells (HUVECs), bone marrow endothelial cells (BMECs), multiple myeloma endothelial cells (MMECs), and MMEC with syndecan-1 silence to form in vitro capillary-like structures and proved that the expression of syndecan-1 promotes in vitro angiogenesis. This evidence concerns the gene SDC1 and plasma cell myeloma.