HIF1A and breast cancer: Our results indicated a boardline connection between HIF-1 rs11549467 and BC risk (AG compared with GG: OR = 1.61, 95% CI = 1.05–2.49, P=0.03; AG + AA compared with GG: OR = 1.64, 95% CI = 1.08–2.51, P=0.02; AG compared with GG + AA: OR = 1.61, 95% CI = 1.04–2.48, P=0.03; OR = 1.64, 95% CI = 1.09–2.45, P=0.02), while HIF-2 rs17039192 had no influence on breast cancer.