IL6 and ductal breast carcinoma in situ: After IL-6 (50 ng/ml) was added to the culture medium of DCIS.com alone for 48 h, DCIS.com proliferation (1.14 ± 0.01, P < 0.0001) and migration (1.33 ± 0.07, P = 0.002) were significantly increased compared to those of the control cells (Fig. 4a).