These genes include the neutrophil chemokines Cxcl5, Ccl4 and Cxcl1, as well as the T cell chemokines Ccl5, Cxcl10 and Ccl17. Gonorrhea’s strong inflammatory reaction was also reflected in this phase-independent anti-GC response with classic proinflammatory mediators like Il1a and Il1b, Ltb (Lymphotoxin Beta), and Tnf (TNF-α) found among the leading-edge genes. This evidence concerns the gene IL1A and gonorrhea.