Results from a study using Sprague-Dawley rats where resveratrol was given in the diet two weeks before vein injection with the tumor-initiating agent 7,12-dimethylbenz(a)anthracene (DMBA) demonstrated that resveratrol acts as a strong antioxidant and significantly induces apoptosis with concomitant upregulation of TGFβ1 expression and inhibition of NF-κB in these carcinogen-challenged animals (Chatterjee et al. 2011). Here, TGFB1 is linked to neoplasm.