This effect was most likely a result of inhibition of NF-κB activity and transcriptional downregulation of AP-1 and downregulation of cyclin D1, COX-2, and MMP-9, which further leads to inhibition of the breast cancer cell metastasis (Aggarwal et al. 2005; Kim et al. 2012). This evidence concerns the gene NFKB1 and breast carcinoma.