ACO1 and metabolic dysfunction-associated steatohepatitis: The answer might have come from Hoki et al. study, where high levels of hepcidin in NASH were associated with iron-overload due to increased divalent metal transporter 1 (DMT1) expression in enterocytes through increased acitivity of iron-regulatory protein 1 (IRP1) (Hoki et al. 2015).