HAMP and infection: Differences in pathophysiological mechanisms induced by HBV and HCV explain why hepcidin levels have a specific mode of fluctuation in these infections; they include differences in the level of oxidative stress, co-infection with hepatitis D, level of viral load, presence of inflammation (Aoki et al. 2005; Fujita et al. 2008; Sebastiani et al. 2012; Wang et al. 2013).