Another circRNA that might be important in lymphomagenesis is circAmotl1, which has been shown to trigger tumourigenesis through nuclear translocation of MYC and upregulation of MYC targets [144]; however, no studies have yet examined whether circAmotl1 is an important oncogenic driver in B-cell malignancies with high MYC expression such as BL or DLBCL. This evidence concerns the gene MYC and diffuse large B-cell lymphoma.