The median serum levels of MALAT1 in the HCC group were higher when compared to the cirrhotic (2.54 vs. 0.70; p = 0.043) and healthy groups (2.54 vs. 0.32; p = 0.025); however, no significant differences were observed between the cirrhotic and healthy groups. The gene discussed is MALAT1; the disease is hepatocellular carcinoma.