MEG3 and metabolic dysfunction-associated steatotic liver disease: In our own unpublished work, we observed a slight upregulation in liver tissue from NAFLD fibrosis patients when compared to those with normal liver histology; however, we found significant downregulation of MEG3 in activated LX-2 cells compared to quiescent cells, suggesting that this lncRNA may contribute to fibrosis through HSC-dependent mechanisms.