MALAT1 and metabolic dysfunction-associated steatohepatitis: Levels of MALAT1 in paired liver biopsies taken at least five years apart showed an eight-fold increase in one patient who progressed from steatosis to NASH fibrosis and a 29-fold increase in another patient who progressed from fibrosis 0 (no fibrosis) to fibrosis 3 (advanced fibrosis).