Practical molecular classification of endometrial cancer, according to PLS and p53 staining results (PLS 3-tier classification) revealed that the best PFS and OS in sporadic cancer with wild type p53, followed by PLS, and finally, sporadic cancer with mutation type p53 (p = 0.033, <0.001) (Figure 4C,D). Here, TP53 is linked to endometrial cancer.