TP53 and head and neck squamous cell carcinoma: These Ad-p53 vectors known as Advexin (Introgen Therapeutics, Multivir, Inc, both of Houston, TX), SCH58500 (Merck & Co; Schering-Plough, Kenilworth, NJ) and Gendicine (Shenzhen SiBiono GeneTech, Guangdong, China) have been tested for treating different types of cancers, including non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC), colorectal, bladder and several other cancers 51,.