USP33 and infection: In Fig 8C, PSMA3 that is expressed at a low level positively interacts with the human TF STAT3 (also at a low level of expression) (p-value = 8.98 × 10−13) via ST3GAL3, and STAT3 is subjected to ubiquitination by ubiquitin protein USP33 so that human STAT3 has low activity (p-value = 1.35 × 10−23) with regard to reducing the suppression of lytic infection and decreasing the transcriptional inhibition of the human target gene NRP1. Human NRP1 is highly active (p-value = 1 × 10−80) and is able to transport and assist in EBV virion translocation.