We and others have previously reported a decreased rate of fusion in human PINK1 and DJ‐1 knockdown cells and that this phenotype can be reversed by downregulating the fission protein Drp1.25, 36, 37, 38 In the current study, we investigate how PINK1 or DJ‐1 knockdown affect mitochondrial transport in a human, RA/BDNF differentiated neuroblastoma model. The gene discussed is PARK7; the disease is neuroblastoma.