CCR6 and Arthritis: In patients with RA, CCR6 expression on monocytes has been shown to correlate with the potential of monocytes to differentiate into osteoclasts ex vivo, suggesting a possible role of CCR6 on monocytes in the recruitment of osteoclast precursors to the joint.20 However, despite the evidence for the importance of CCR6 in various cell types, which are known drivers for the development of RA, the role of CCR6 in the development of arthritis beyond T cell‐dependent mechanisms has not been addressed.