Moreover, Helicobacter pylori could probably trigger AIP via molecular mimicry in genetically predisposed individuals due to the significant homology between human carbonic anhydrase II and alpha-carbonic anhydrase of Helicobacter pylori with the homologous segments containing the binding motif of the HLA molecule DRB1*0405 [46]. Here, CA2 is linked to autoimmune pancreatitis.