PIEZO2 and respiratory system disorder: These cases include PIEZO2 (a subtype of distal arthrogryposis, a musculoskeletal contracture and respiratory disease),23LOX (familial aortic dissection),29WISP3 (precocious arthritis),30CHST11 (T cell lymphoma with limb abnormalities),31 complement factor C3 gene (Chopra et al., manuscript in preparation), several cases of undiagnosed craniofacial dysmorphoses, and a gene that causes a rare form of lung cancer (Frank et al., manuscript in preparation) among others.