Furthermore, the histological analysis of the lungs on day 14 after infection showed massive multiplication of yeast cells with poor granulomatous responses in the alveolar spaces of CARD9-deficient mice (Figure 7C), which is consistent with the findings observed in infected Dectin-3-deficient mice with C.g-B strain ATCC32609 (Figure 5C). Here, CLEC4D is linked to infection.