Gao et al. and Huang et al. examined the ins gene in type II diabetic patients and found that the expression of the ins gene in type II diabetes patients was changed compared with that in normal patients and other illnesses, indicating that the change of the ins gene may be one of the causes of type II diabetes (Gao et al., 2016; Huang et al., 2017). Here, INS is linked to type 2 diabetes mellitus.