CD31 expression was decreased in diabetic hearts (NDM vs. DM: 1.711 ± 0.1021 vs. 1.083 ± 0.0359, P < 0.05), while was increased in DM + PKK group (DM vs. DM + PKK: 1.083 ± 0.03592 vs. 1.510 ± 0.0722, P < 0.05, Figure 7C). Here, PECAM1 is linked to diabetes mellitus.